Located in the McGowan Institute for Regenerative Medicine resesarch building at the University of Pittsburgh, the Advanced Imaging Center is a high-field preclinical and molecular magnetic resonance imaging (MRI) and spectroscopy (MRS) facility that houses two high field scanners, a Bruker Biospec 9.4 Tesla 30 cm scanner and a Bruker 11.7 Tesla microimaging system. These scanners are equipped with state-of-the-art multi-channel RF coils, allowing high-resolution in vivo rodent imaging for application in life science, biomedical and preclinical research. The facility has a surgical suite available to perform preparation procedures for the in vivo imaging studies. The facility provides expert faculty and comprehensive imaging support services for investigators from the University of Pittsburgh and other Institutions.
Detection of aberrant hippocampal mossy fiber connections: Ex vivo mesoscale diffusion MRI and microtractography with histological validation in a patient with uncontrolled
Chemical exchange-sensitive spin-lock (CESL) MRI of glucose and analogs in brain tumors.
Jin T, Iordanova B, Hitchens TK, Modo M, Wang P, Mehrens H, Kim SG. Magn Reson
Effects of DHA on Hippocampal Autophagy and Lysosome Function After Traumatic Brain Injury.
Yin Y, Li E, Sun G, Yan HQ, Foley LM, Andrzejczuk LA, Attarwala IY, Hitchens
Metabolic and Structural Imaging at 7 Tesla After Repetitive Mild Traumatic Brain Injury in Immature Rats.
Fidan E, Foley LM, New LA, Alexander H, Kochanek PM, Hitchens
Reactive oxygen species scavenging with a biodegradable, thermally responsive hydrogel compatible with soft tissue injection.
Zhu Y, Matsumura Y, Velayutham M, Foley LM
The influence of suturectomy on age-related changes in cerebral blood flow in rabbits with familial bicoronal suture craniosynostosis: A quantitative analysis.
Grandhi
Detection of aberrant hippocampal mossy fiber connections: Ex vivo mesoscale diffusion MRI and microtractography with histological validation in a patient with uncontrolled temporal lobe epilepsy
Michel Modo, T. Kevin Hitchens, Jessie R. Liu, and R. Mark Richardson Hum Brain Mapp. 2016 Feb; 37(2): 780–795. For PMC full text article click here.
Chemical exchange-sensitive spin-lock (CESL) MRI of glucose and analogs in brain tumors.
Jin T, Iordanova B, Hitchens TK, Modo M, Wang P, Mehrens H, Kim SG. Magn Reson Med. 2018 Aug;80(2):488-495. Pubmed Abstract
Effects of DHA on Hippocampal Autophagy and Lysosome Function After Traumatic Brain Injury.
Yin Y, Li E, Sun G, Yan HQ, Foley LM, Andrzejczuk LA, Attarwala IY, Hitchens TK, Kiselyov K, Dixon CE, Sun D. Mol Neurobiol. 2018 Mar;55(3):2454-2470. Pubmed Abstract
Metabolic and Structural Imaging at 7 Tesla After Repetitive Mild Traumatic Brain Injury in Immature Rats.
Fidan E, Foley LM, New LA, Alexander H, Kochanek PM, Hitchens TK, Bayır H. ASN Neuro. 2018. Pubmed Abstract
Reactive oxygen species scavenging with a biodegradable, thermally responsive hydrogel compatible with soft tissue injection.
Zhu Y, Matsumura Y, Velayutham M, Foley LM, Hitchens TK, Wagner WR. Biomaterials. 2018. Pubmed Abstract.
The influence of suturectomy on age-related changes in cerebral blood flow in rabbits with familial bicoronal suture craniosynostosis: A quantitative analysis.
Grandhi R, Peitz GW, Foley LM, Bonfield CM, Fellows-Mayle W, Hitchens TK, Mooney MP. PLoS One. 2018 Jun 1;13(6). Pubmed Abstract